September 10th, 2025
In recent years, CBD has exploded in popularity, showing up in everything from oils and gummies to bath bombs and coffee. Promoted as a natural remedy for anxiety and depression, many people are turning to CBD in search of relief from mental health symptoms.
But does CBD actually work for anxiety and depression? And how much do we really know about its safety and effectiveness?
In this blog, we explore what the research says, how CBD interacts with the brain, and whether it’s a viable option for managing mental health symptoms.
CBD, short for cannabidiol, is a naturally occurring compound found in the cannabis plant. Unlike THC (tetrahydrocannabinol), CBD does not produce a “high” or alter your state of mind.
CBD is often extracted from hemp and is used in various forms—such as oils, capsules, edibles, and topicals—to support wellness. It's widely marketed for its potential calming effects, with many people using it to help manage symptoms like anxiety, stress, insomnia, and chronic pain.
While CBD is legal in many states and available over the counter, it’s important to note that its effects can vary and more research is still needed to fully understand its benefits and risks.
While more research is needed to fully understand its effects, early studies suggest that CBD may hold promise in supporting a range of conditions, including anxiety, depression, epilepsy, and sleep disturbances. Though not a cure or a substitute for professional care, CBD is increasingly viewed as a complementary option within the broader mental health and wellness space.
Early studies and anecdotal reports suggest that CBD may help:
Again, while CBD is not a replacement for professional mental health treatment, its growing popularity reflects a broader interest in holistic and accessible wellness options. It's often used alongside other supports like therapy, medication, or mindfulness practices.
One of the most common reasons people turn to CBD is to help manage anxiety symptoms. Whether it’s chronic worry, social anxiety, or occasional stress, users may report feeling calmer and more at ease after taking CBD.
Some early research supports these claims—studies suggest that CBD may influence how the brain responds to serotonin, a neurotransmitter linked to mood and anxiety regulation. CBD has shown potential in reducing symptoms of generalized anxiety disorder, social anxiety, and even panic disorder.
That said, CBD affects everyone differently, and it’s not a guaranteed solution. Dosage, product quality, and individual body chemistry all play a role in its effectiveness.
If anxiety is interfering with your daily life, it’s always best to consult with a mental health professional before starting any new treatment—including CBD.
Resources: If you are struggling with anxiety and would like to attend a support group, Clarity Clinic offers a virtual anxiety support group for adults every Thursday at 5pm. Click HERE for more information
CBD is also being explored for its potential role in easing symptoms of depression. Some studies suggest that CBD may have mood-stabilizing and antidepressant-like effects by interacting with the body’s endocannabinoid system and serotonin receptors—both of which play a role in regulating mood. Cannabidiol does not seem to increase serotonin levels, instead it seems to affect how the brain responds to pre-existing serotonin.
Unlike traditional antidepressants, CBD is not known to cause significant side effects like weight gain or sexual dysfunction, which makes it appealing to some individuals seeking alternative options. However, it's important to note that CBD is not a substitute for professional treatment, especially for moderate to severe depression.
For those experiencing ongoing low mood, hopelessness, or loss of interest in daily life, CBD might serve as a complementary option—but it should be discussed with a mental health provider to ensure safety and effectiveness.
CBD works by interacting with the body’s endocannabinoid system (ECS)—a complex network of receptors that helps regulate mood, stress response, sleep, and other functions. Specifically, CBD is believed to influence serotonin receptors (5-HT1A) in the brain, which play a key role in mood and anxiety regulation.
Early studies have shown that CBD may:
While these findings are promising, it’s important to note that most research has been conducted on animals or in small human trials, and CBD is not yet approved by the FDA for treating anxiety or depression. More large-scale studies are needed to confirm its long-term safety and effectiveness.
The FDA has not yet approved any over-the-counter (OTC) CBD product. However, here are the common ways that CBD is presented:
It’s important to note that while CBD products are legal in many states, they are still illegal in some.
It is essential that you talk to your doctor before taking any CBD products. This is especially important if you are currently taking any medications or have an existing psychiatric or medical condition.
It's vital to remember that CBD isn't risk-free. While some people find relief from symptoms, CBD may interact with certain medications or affect mental health conditions differently. In some cases, it can actually worsen symptoms like anxiety, disrupt sleep, or even intensify issues related to psychosis.
Before trying any new treatment—including CBD—it’s best to consult with your healthcare provider to ensure it’s safe and appropriate for your specific needs.
Disclaimer: The information on this page is for educational and informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with any questions regarding a medical condition or treatment. Never ignore or delay seeking professional help due to information found here.
At Clarity Clinic, we provide compassionate, evidence-based care for individuals struggling with anxiety and depression. Whether you're just beginning your mental health journey or need a higher level of support, our team is here to help you find the right treatment path.
We offer a full range of services, including therapy services, psychiatry services, TMS therapy for depression, and structured care through our Partial Hospitalization Program (PHP) and Intensive Outpatient Program (IOP).
Our PHP and IOP programs are designed for those whose anxiety and depression symptoms require more than once-a-week therapy, offering a supportive, therapeutic environment without the need for hospitalization.
If you’ve been searching for an intensive outpatient program for depression near you or a trusted PHP program in Chicago, Clarity Clinic is here to help. Our IOP for depression and anxiety, as well as our partial hospitalization program near you, provide flexible care to help you regain stability and improve your quality of life.
At Clarity:
Explore our mental health clinic locations: Loop, River North, Lakeview Belmont, Lakeview Broadway, Arlington Heights, Evanston
Find Mental Health SupportPHP/IOP Mental Health Program for Anxiety & Depression: More Information
Related Readings:
Is it better to take CBD instead of antidepressants?
Not necessarily. Antidepressants are well-researched, FDA-approved treatments for depression. CBD is still being studied, and while some people report benefits, it is not a replacement for prescribed medication. Always talk to your doctor before changing treatment.
How much CBD should I take for depression?
There is no standard or FDA-approved dosage of CBD for depression. Amounts can vary widely based on the product, strength, and individual response. It’s best to talk with a healthcare professional before beginning any new treatment for depression.
What is the best medication for depression?
The best medication for depression depends on the individual. What works well for one person might not work for another, as everyone is unique and requires tailored treatment. Common options include SSRIs (like Prozac or Zoloft), SNRIs (like Cymbalta), and other antidepressants. A doctor can help choose the right fit based on symptoms, side effects, and health history.
Can CBD help with mental health issues?
Some research suggests CBD may help with anxiety, sleep problems, and mood. However, evidence is very limited, and CBD is not a proven treatment for depression or other psychiatric conditions.
Who should avoid taking CBD?
Pregnant or breastfeeding women, people taking certain medications (like blood thinners), and those with liver problems should avoid CBD unless cleared by a doctor. In general, you should consult with your doctor before taking CBD.
Which CBD is best for anxiety and depression?
There is no single “best” CBD for mental health. Products differ in strength, purity, and formulation. CBD is not FDA approved for anxiety or depression, it is best to consult a healthcare provider before use.
Does CBD help with anxiety?
CBD may help reduce anxiety for some people, but research is still limited. It’s not an FDA-approved treatment, so talk to your doctor before using it.
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